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Prevalence estimates of seasonal affective disorder (SAD) in Iceland from the 90s were comparably low at 3.8%. Prior research suggests that risk factors for SAD are young age, evening chronotype, reduced physical activity, cognitive vulnerabilities, and specific neurophysiological patterns of brain activity. In addition, air pollution was found to induce depression and air pollution undergoes regional and seasonal fluctuations. So far, the interaction of these factors has not been examined and air pollution has been ignored. In the EPiC SAD study we started in 2022 by conducting a large survey, starting with N=15000 people living in Iceland from which around 2000 participated to study the current prevalence of SAD.
From these participants, about 200 joined a longitudinal study which is completed in 2025, half of them being vulnerable to seasonal changes, the other half being unaffected. We followed this sample 4 times a year with questionnaires and recordings of brain recordings, as well as measurements of air pollution in their home. At each follow-up we conducted an emotional memory task, examined chronotype, cognitive vulnerabilities, nutrition, health-related quality of life, physical activity, sleep quality, daily fluctuations of mood and individual exposure to air pollution. The data is currently used to build a prediction model for early identification of the at-risk population.
This project is funded by the Icelandic Research Fund (appl. Nr. 228739-051/ 2106-0364)
Students: Angantýr Ómar Ásgeirsson, Angelina Brigitte Carlucci, Anna Kristrún Sigurpálsdóttir, Ara Dan Pálmadóttir, Ásta Guðrún Birgisdóttir, Dagný Theódórsdóttir, Gestur Vagn Baldursson, Harpa Hlin Gunnarsdóttir, Helgi Brynjólfsson, Hilde Björk Didriksen Smith, og Marín Rut Bech Ingadóttir eru nemendur sem munu vinna ritgerðir sínar innan verkefnisins.